Short communication. IL-1 family members as possible candidate genes affecting economically important traits in cattle

  • A. Marcos-Carcavilla INIA. Madrid
  • J.H. Calvo Unidad de Tecnología en Producción Animal, CITA. Zaragoza
  • C. González . Matanzas
  • C. González INIA. Madrid
  • K. Moazami-Goudarzi Laboratoire de Génétique biochimique et de Cytogénétique, INRA. Jouy-en-Josas, Cedex
  • P. Laurent Laboratoire de Génétique biochimique et de Cytogénétique, INRA. Jouy-en-Josas, Cedex
  • M. Bertaud Laboratoire de Génétique biochimique et de Cytogénétique, INRA. Jouy-en-Josas, Cedex
  • H. Hayes Laboratoire de Génétique biochimique et de Cytogénétique, INRA. Jouy-en-Josas, Cedex
  • M.E.F. Alves INIA. Madrid
  • M. Serrano INIA. Madrid
  • M. Serrano EPSO, University Miguel Hernández. Orihuela
Keywords: CATTLE, GENES, ANIMAL BREEDING, SELECTION CRITERIA, CYTOKINES, INTERLEUKINS, ANIMAL HEALTH, MEAT YIELD

Abstract

Health problems in cattle cause considerable economic losses for the producers. Proinflammatory cytokines have been shown to play important roles in different aspects of animal health and production. In the present work, interleukin-1 beta and interleukin-1 receptor antagonist genes (IL1B and IL1RN, respectively) have been localized on bovine chromosome 11 (BTA11q22). The precise location for IL1RN is reported and discrepancies concerning the exact position of IL1B (BTA 11q22 or BTA 11q23/11q24) are solved. In addition, the BTA11q22 region has been shown to carry several quantitative trait loci intervals affecting cattle production. Thus, it may be interesting to consider these two cytokines in order to develop more efficient breeding schemes and improve the accuracy and intensity of selection programs.

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Published
2007-03-01
How to Cite
Marcos-Carcavilla, A., Calvo, J., González, C., González, C., Moazami-Goudarzi, K., Laurent, P., Bertaud, M., Hayes, H., Alves, M., Serrano, M., & Serrano, M. (2007). Short communication. IL-1 family members as possible candidate genes affecting economically important traits in cattle. Spanish Journal of Agricultural Research, 5(1), 38-42. https://doi.org/10.5424/sjar/2007051-228
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